What is Small Volume Blood (SVB)

Small Volume Blood (SVB) for our testing platform is defined as any collection that is less than 0.5 mL of whole blood. By utilizing the latest in tandem mass spectrometry and robotic sample preparation; the total volume needed to generate accurate and reproducible results has been significantly reduced compared to traditional blood testing methodology. With our current technology, the hormone panel only requires 0.15 ml of serum/plasma, and our toxicology panel requires only 0.1 mL of serum/plasma to achieve precise and accurate clinical results. Despite using less sample volume, our method has shown to correlate very well against traditional methods. 

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Testosterone Hormone

“Ovulation results in a mid-cycle surge of luteinizing hormone (LH) followed by an increase in progesterone secretion, peaking between day 21 and 23. If no fertilization and implantation has occurred by then, supplying the corpus luteum with human gonadotropin-drive growth stimulus, progesterone secretion falls, ultimately triggering menstruation.

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Progesterone Hormone

Ovulation results in a mid-cycle surge of luteinizing hormone (LH) followed by an increase in progesterone secretion, peaking between day 21 and 23. If no fertilization and implantation has occurred by then, supplying the corpus luteum with human gonadotropin-drive growth stimulus, progesterone secretion falls, ultimately triggering menstruation.

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Estriol Hormone

Of the three major estrogens (estrone [e1], estradiol [e2], estriol [e3]), is the least potent natural estrogen (E2 > E1 > E3). In men and non-pregnant women, E1 and E2 are formed from androstenedione and testosterone. E3 is synthesized from E2 and to a limited extent, from 16-alpha metabolites of estrone.

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Estrone Hormone

Estrone is one of two major estrogens in non-pregnant women and is a major estrogen produced by the placenta.22 The primary ovarian estrogen is estradiol; circulating estrone is derived from ovarian secretion and peripheral conversion from gonadal and adrenal androstenedione (via CYP450 aromatase in lipid tissue)

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